by Kharrazian Institute | Aug 15, 2026 | Blog, Mood and Anxiety
The serotonin hypothesis of depression has driven psychiatric treatment for decades. It has also produced a patient population that takes SSRIs indefinitely, never fully recovers, and cycles through medication adjustments while the underlying physiology goes...
by Kharrazian Institute | Aug 14, 2026 | Blog, Mood and Anxiety
Most practitioners treating depression are still asking one question: which neurotransmitter is deficient? Research in neuroimmunology has been asking a different one for years: which inflammatory pathway is active? The clinical gap between those two questions is...
by Kharrazian Institute | Aug 13, 2026 | Blog, Cognitive Decline and Dementia
Most practitioners ordering a cognitive workup are asking one question: is this Alzheimer’s or isn’t it? That’s the wrong question. Cognitive decline has a differential diagnosis as broad and mechanistically distinct as any other complex chronic...
by Kharrazian Institute | Aug 12, 2026 | Blog, Cognitive Decline and Dementia
A practitioner’s most common mistake with dementia patients is treating the brain last. The gut gets addressed, the liver gets supported, the hormones get balanced — and the organ driving the patient’s decline receives the least direct clinical attention....
by Kharrazian Institute | Aug 11, 2026 | Blog, Childhood Development
Most practitioners understand that early childhood matters for brain development. Fewer appreciate how precisely timed that window is — or how many distinct biological systems must converge correctly within it. The Kharrazian Institute’s pediatric...
